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Chantest Inc whole-cell patch clamp experiments
Whole Cell Patch Clamp Experiments, supplied by Chantest Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/patch-clamp+experiments/patch+clamp+assay/pmc07527709-376-16-7
Average 90 stars, based on 1 article reviews
whole-cell patch clamp experiments - by Bioz Stars, 2026-10
90/100 stars

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Article Title: Imidazol-1-ylethylindazole Voltage-Gated Sodium Channel Ligands Are Neuroprotective during Optic Neuritis in a Mouse Model of Multiple Sclerosis
Article Snippet: Nav Isoform Screening: Patch-clamp experiments against hNav1.1 to hNav1.8/β3 were performed by Chantest Inc., Cleveland, OH.

Article Title: Oxadiazolylindazole sodium channel modulators are neuroprotective toward hippocampal neurones.
Article Snippet: We report the discovery of a new class of neuroprotective voltage-dependent sodium channel modulators exemplified by (5-(1-benzyl-1H-indazol-3-yl)-1,2,4-oxadiazol-3-yl)methanamine 11 (CFM1178).. The compounds were inhibitors of [14C]guanidinium ion flux in rat forebrain synaptosomes and displaced binding of the sodium channel ligand [3H]BW202W92.. 11 and the corresponding N2-benzyl isomer, 38 (CFM6058), demonstrated neuroprotective activity in hippocampal slices comparable to sipatrigine.



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